Open AccessThermodynamics of B-Z transition in supercoiled DNA
Author(s) -
Srikanta Sen,
Rabi Majumdar
Publication year - 1987
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/15.14.5863
Subject(s) - dna supercoil , transition (genetics) , biology , dna , thermodynamics , physics , biophysics , genetics , gene , dna replication
The nature of the possible supercoil-induced B-Z transition has been analyzed from the thermodynamical point of view, by taking into account the effects of the twisting as well as the writhing components of the supercoiling free energy. The cooperative aspects of the transition, as predicted by theory, agrees well with the corresponding experimental data.
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