A new repetitive element of the CRI family downstream of the chicken vitellogenin gene | Zendy

Fred het van Schip | Zendy; John Samallo | Zendy; Frits Meijlink | Zendy; Max Gruber | Zendy; Geert AB | Zendy

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A new repetitive element of the CRI family downstream of the chicken vitellogenin gene

Author(s) -

Fred het van Schip,

John Samallo,

Frits Meijlink,

Max Gruber,

Geert AB

Publication year - 1987

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/15.10.4193

Subject(s) - biology , repeated sequence , gene , vitellogenin , genetics , chromatin , sequence (biology) , hormone response element , dna , microbiology and biotechnology , regulatory sequence , regulation of gene expression , genome , cancer , estrogen receptor , breast cancer

We have analyzed a repetitive DNA sequence found in the 3'-flanking region of the chicken vitellogenin gene. By its sequence, the repetitive DNA has been identified as a hitherto unreported member of the chicken CR1 family of repetitive elements. The CR1 sequence displays the structural characteristics of a long terminal repeat located at the 3' end of an avian retrovirus. The CR1 element lies 2.2 kb downstream of the vitellogenin gene and 'points' away from the gene rather than toward it. In this respect, this element differs from other CR1 repeats. The CR1 element is embedded in a region showing changes in chromatin structure implying a potential role for this sequence in determining the structural state of the local chromatin.

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