A novel GC-rich dispersed repeat sequence inDrosophila melanogaster | Zendy

Andrew J. Flavell | Zendy; Julian Dyson | Zendy; David IshHorowicz | Zendy

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A novel GC-rich dispersed repeat sequence inDrosophila melanogaster

Author(s) -

Andrew J. Flavell,

Julian Dyson,

David IshHorowicz

Publication year - 1987

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/15.10.4035

Subject(s) - biology , drosophila melanogaster , genetics , transposable element , genome , homologous chromosome , repeated sequence , southern blot , melanogaster , sequence analysis , polyadenylation , gene , rna

A novel family of dispersed repeat sequences from Drosophila melanogaster is described. Sequence analysis of two members of this family show them to contain greater than 75% GC bases. These are comprised of multiple repeats of GGX triplets interspersed occasionally with CGPy and TTPy. Southern blotting shows that these repeats are not transposable elements. Twenty four homologous recombinants have been localised by in situ hybridization to seven sites in the Drosophila genome. Polyadenylated RNAs homologous to this repeat family are expressed in a complex pattern which is developmentally regulated. We suggest that this family encodes a set of glycine-rich domains in Drosophila proteins.

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