Open AccessLinkage arrangement in the vitellogenin gene family ofXenopus laevisas revealed by gene segregation analysis
Author(s) -
Jean-Luc Schubiger,
Walter Wahli
Publication year - 1986
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/14.22.8723
Subject(s) - biology , xenopus , vitellogenin , gene , genetics , restriction fragment length polymorphism , allele , genetic linkage , gene family , linkage (software) , microbiology and biotechnology , gene expression , polymerase chain reaction
Using restriction fragment length polymorphism (RFLP) we have analyzed the segregation of alleles of the different vitellogenin genes of Xenopus laevis. The results demonstrate that the four genes whose expression is controlled by oestrogen, form two linkage groups. The genes A1, A2 and B1 are linked genetically whereas the fourth gene, the gene B2, segregates independently. The possible origin of this unexpected arrangement is discussed.