Open AccessControl of cell division inEscherichia coli. DNA sequence ofdicAand of a second gene complementing mutationdicA1,dicC
Author(s) -
Samír Béjar,
Kaymeuang Cam,
JeanPierre Bouché
Publication year - 1986
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/14.17.6821
Subject(s) - biology , genetics , escherichia coli , gene , mutation , sequence (biology) , dna , dna sequencing , nucleic acid sequence , microbiology and biotechnology
A mutation in a gene dicA of Escherichia coli leads to temperature-sensitive cell division, by allowing expression of a nearby division inhibition gene dicB (1). We have now established the sequence of the DicA region and identified DicA as a 15.5 KD protein. A second gene dicC transcribed divergently from dicA and coding for an 8.5 KD protein can also complement mutation dicA1 when provided on a multicopy plasmid.