Open AccessNucleotide sequence encoding the biosynthetic dehydroquinase function of the penta-functionalAROMlocus ofAspergillus nidulans
Author(s) -
Ian G. Charles,
John W. Keyte,
William J. Brammar,
Alastair R. Hawkins
Publication year - 1985
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/13.22.8119
Subject(s) - biology , sequence (biology) , nucleic acid sequence , genetics , aspergillus nidulans , function (biology) , sequence analysis , gene , mutant
The nucleotide sequence of a 1.9 Kb HindIII fragment of DNA derived from the arom locus of A.nidulans and encoding the biosynthetic dehydroquinase activity has been determined. The sequences encoding the biosynthetic and catabolic dehydroquinase enzymes of A.nidulans show no detectable homology, strongly suggesting convergent evolutionary pathways. The messenger RNA specified by the arom locus was detected as a 5.3 Kb RNA species.