Open AccessA microcomputer program for analysis of nucleic acid hybridizatoin data
Author(s) -
S. Green,
John K. Field,
C.D. Green,
Robert J. Bey
Publication year - 1982
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/10.4.1411
Subject(s) - biology , nucleic acid , microcomputer , computational biology , genetics , computer science , telecommunications , chip
The study of nucleic acid hybridization is facilitated by computer mediated fitting of theoretical models to experimental data. This paper describes a non-linear curve fitting program, using the 'Patternsearch' algorithm, written in BASIC for the Apple II microcomputer. The advantages and disadvantages of using a microcomputer for local data processing are discussed.