Base specific binding of deoxyguanylate and deoxycytidylate antibodies to double stranded DNA | Zendy

Alexander Jacob | Zendy; T. M. Jacob | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Base specific binding of deoxyguanylate and deoxycytidylate antibodies to double stranded DNA

Author(s) -

Alexander Jacob,

T. M. Jacob

Publication year - 1982

Publication title -

nucleic acids research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 9.008

H-Index - 537

eISSN - 1362-4954

pISSN - 0305-1048

DOI - 10.1093/nar/10.20.6273

Subject(s) - biology , double stranded , dna , antibody , microbiology and biotechnology , base pair , dna binding protein , binding site , biochemistry , genetics , gene , transcription factor

Antibodies raised in rabbits against deoxyguanylate and deoxycytidylate bind to 3H-lambda double stranded DNA and the binding is base specific. The concentrations of antibody populations that bind to double stranded DNA are much less than those binding to denatured DNA. Due to their low concentrations, these antibodies were not detected in earlier studies. These antibodies are expected to be useful to probe the conformational flexibilities of double stranded DNAs.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research