Open AccessNucleotide sequence of a region of the mitochondrial genome ofAspergillus nidulansincluding the gene for ATPase subunit 6
Author(s) -
E. Grisi,
Terence A. Brown,
Richard B. Waring,
Claudio Scazzocchio,
R. Wayne Davies
Publication year - 1982
Publication title -
nucleic acids research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 9.008
H-Index - 537
eISSN - 1362-4954
pISSN - 0305-1048
DOI - 10.1093/nar/10.11.3531
Subject(s) - biology , genetics , gene , aspergillus nidulans , nucleic acid sequence , homology (biology) , open reading frame , protein subunit , microbiology and biotechnology , peptide sequence , mutant
A 1500 bp fragment of the Aspergillus nidulans mitochondrial genome contains genes for arginine and asparagine tRNAs, an unassigned reading frame, and the structural gene for ATPase subunit 6. The tRNA genes possess 66% nucleotide homology and possibly originated by a relatively recent duplication event. The unassigned reading frame displays a low level of homology with the human URF A6L. The predicted amino acid sequence of the A-nidulans ATPase subunit 6 gene is 40% homologous to the yeast polypeptide and includes the short, highly conserved regions also present in the equivalent subunits from other mitochondrial systems and from Escherichia coli.