Open AccessA Ca2+ cycling defect connects insulin resistance and heart failure
Author(s) -
Qian Shi,
Duane D. Hall,
LongSheng Song
Publication year - 2022
Publication title -
life metabolism
Language(s) - English
Resource type - Journals
ISSN - 2755-0230
DOI - 10.1093/lifemeta/loac014
Subject(s) - insulin resistance , heart failure , intracellular , medicine , insulin , cycling , cardiomyopathy , cardiology , endocrinology , microbiology and biotechnology , biology , history , archaeology
In a recent study published in Life Metabolism , Quan et al . reported that intracellular Ca 2+ dysregulation in cardiomyocyte can be both a cause and an effect of cardiac insulin resistance that ultimately leads to diabetic cardiomyopathy.