Open AccessOvarian malignant mixed Müllerian tumor: a rare case report from Tanzania
Author(s) -
Angela Pallangyo,
Jeremia J Pyuza,
Alice A Andongolile,
Daniel Mbwambo,
Jackson P Claver,
Ummil-Khairat Koosa,
Kennedy Lema,
Patrick Amsi,
Gilbert Nkya,
Alex Mremi
Publication year - 2020
Publication title -
journal of surgical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.14
H-Index - 3
ISSN - 2042-8812
DOI - 10.1093/jscr/rjaa406
Subject(s) - medicine , histopathology , debulking , ovary , immunostaining , pathology , abdomen , ovarian cancer , adnexal mass , stage (stratigraphy) , cancer , rare disease , radiology , immunohistochemistry , disease , paleontology , biology
Malignant mixed Müllerian tumor of the ovary is rare aggressive tumor that is histologically defined by the presence of malignant epithelial and stromal components. We report a 37-year-old woman who consulted our facility complaining of abdominal distention and a painful palpable mass over her lower abdomen. Physical examination including computerized tomography revealed a complex cystic mass lesion on the left ovary with extensive omental involvement. Ovarian cancer was suspected and the patient underwent debulking surgery. The histopathology of the specimen revealed a high-grade tumor composed of both malignant epithelial and sarcomatous elements. Both epithelial and stromal components stained positive for p53 immunostaining. Before the initiation of chemotherapy, on 5th day postoperation, the patient was found unresponsive. The stage of the disease seems to be the most important prognostic factor, thus emphasis should be made to identify it in earlier stages.