Open AccessFukushima simulation experiment: assessing the effects of chronic low-dose-rate internal137Cs radiation exposure on litter size, sex ratio, and biokinetics in mice
Author(s) -
Hiroo Nakajima,
Yoshiaki Yamaguchi,
Takashi Yoshimura,
Manabu Fukumoto,
Tomoki Todo
Publication year - 2015
Publication title -
journal of radiation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.643
H-Index - 60
eISSN - 1349-9157
pISSN - 0449-3060
DOI - 10.1093/jrr/rrv079
Subject(s) - litter , internal radiation , fukushima nuclear accident , zoology , internal dose , nuclear medicine , chemistry , radiochemistry , toxicology , medicine , nuclear power plant , biology , ecology , physics , nuclear physics
To investigate the transgenerational effects of chronic low-dose-rate internal radiation exposure after the Fukushima Daiichi Nuclear Power Plant accident in Japan, 18 generations of mice were maintained in a radioisotope facility, with free access to drinking water containing (137)CsCl (0 and 100 Bq/ml). The (137)Cs distribution in the organs of the mice was measured after long-term ad libitum intake of the (137)CsCl water. The litter size and the sex ratio of the group ingesting the (137)Cs water were compared with those of the control group, for all 18 generations of mice. No significant difference was noted in the litter size or the sex ratio between the mice in the control group and those in the group ingesting the (137)Cs water. The fixed internal exposure doses were ∼160 Bq/g and 80 Bq/g in the muscles and other organs, respectively.