Open AccessLimiting Vancomycin Exposure in Pediatric Oncology Patients With Febrile Neutropenia May Be Associated With Decreased Vancomycin-Resistant Enterococcus Incidence
Author(s) -
Manjiree Karandikar,
Carly E. Milliren,
Robin Zaboulian,
Poornima Peiris,
Tanvi Sharma,
Andrew E. Place,
Thomas J. Sandora
Publication year - 2019
Publication title -
journal of the pediatric infectious diseases society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.269
H-Index - 31
eISSN - 2048-7207
pISSN - 2048-7193
DOI - 10.1093/jpids/piz064
Subject(s) - medicine , febrile neutropenia , incidence (geometry) , vancomycin , guideline , neutropenia , antimicrobial stewardship , bacteremia , intensive care medicine , antibiotics , pediatrics , chemotherapy , antibiotic resistance , pathology , physics , microbiology and biotechnology , biology , bacteria , optics , genetics , staphylococcus aureus
Limited data exists regarding the effects of empiric antibiotic use in pediatric oncology patients with febrile neutropenia (FN) on the development of antibiotic resistance. We evaluated the impact of a change in our empiric FN guideline limiting vancomycin exposure on the development of vancomycin-resistant Enterococcus in pediatric oncology patients.