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The Impact of Social Distancing for COVID-19 Upon Diagnosis of Kawasaki Disease
Author(s) -
Stanford T. Shulman,
Bessey Geevarghese,
KwangYoun A. Kim,
Anne H. Rowley
Publication year - 2021
Publication title -
journal of the pediatric infectious diseases society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.269
H-Index - 31
eISSN - 2048-7207
pISSN - 2048-7193
DOI - 10.1093/jpids/piab013
Subject(s) - kawasaki disease , medicine , covid-19 , respiratory system , etiology , disease , intensive care medicine , medical diagnosis , pandemic , respiratory illness , coronavirus , pediatrics , pathology , infectious disease (medical specialty) , artery
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mitigation policies have been associated with profound decreases in diagnoses of common childhood respiratory infections. A leading theory of etiology of Kawasaki disease (KD) is that it is triggered by presently unidentified ubiquitous respiratory agent. We document that mitigation policies instituted in mid-March 2020 were associated with strikingly fewer diagnoses of KD in April-December 2020 compared with the same period in the previous 8 years (P = .01), a >67% decline. This finding supports the hypothesis that KD is caused by a respiratory-transmitted agent.

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