Open AccessHIV RNA, CD4+ Percentage, and Risk of Hepatocellular Carcinoma by Cirrhosis Status
Author(s) -
J Torgersen,
Michael J. Kallan,
Dena M. Carbonari,
Lesley S. Park,
Rajni Mehta,
Kathryn D’Addeo,
Janet P. Tate,
Joseph K. Lim,
Matthew Bidwell Goetz,
Maria C. RodriguezBarradas,
Cynthia Gibert,
Norbert Bräu,
Sheldon T. Brown,
Jason Roy,
Tamar H. Taddei,
Amy C. Justice,
Vincent Lo Re
Publication year - 2019
Publication title -
journal of the national cancer institute
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.797
H-Index - 356
eISSN - 1460-2105
pISSN - 0027-8874
DOI - 10.1093/jnci/djz214
Subject(s) - medicine , hepatocellular carcinoma , cirrhosis , hazard ratio , viremia , proportional hazards model , gastroenterology , cohort , incidence (geometry) , confidence interval , viral load , cohort study , immunology , human immunodeficiency virus (hiv) , physics , optics
Despite increasing incidence of hepatocellular carcinoma (HCC) among HIV-infected patients, it remains unclear if HIV-related factors contribute to development of HCC. We examined if higher or prolonged HIV viremia and lower CD4+ cell percentage were associated with HCC.