Early-Life Body Adiposity and the Breast Tumor Transcriptome | Zendy

Jun Wang | Zendy; Cheng Peng | Zendy; Catherine Guranich | Zendy; Yujing J. Heng | Zendy; Gabrielle M. Baker | Zendy; Christopher A. Rubadue | Zendy; Kimberly Glass | Zendy; A. Heather Eliassen | Zendy; Rulla M. Tamimi | Zendy; Kornélia Polyák | Zendy; Susan E. Hankinson | Zendy

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Early-Life Body Adiposity and the Breast Tumor Transcriptome

Author(s) -

Jun Wang,

Cheng Peng,

Catherine Guranich,

Yujing J. Heng,

Gabrielle M. Baker,

Christopher A. Rubadue,

Kimberly Glass,

A. Heather Eliassen,

Rulla M. Tamimi,

Kornélia Polyák,

Susan E. Hankinson

Publication year - 2020

Publication title -

jnci journal of the national cancer institute

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.797

H-Index - 356

eISSN - 1460-2105

pISSN - 0027-8874

DOI - 10.1093/jnci/djaa169

Subject(s) - transcriptome , downregulation and upregulation , pi3k/akt/mtor pathway , biology , cancer research , breast cancer , estrogen receptor , estrogen receptor alpha , endocrinology , medicine , cancer , signal transduction , gene , gene expression , microbiology and biotechnology , genetics

Cumulative epidemiologic evidence has shown that early-life adiposity is strongly inversely associated with breast cancer risk throughout life, independent of adult obesity. However, the molecular mechanisms remain poorly understood.

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