Open AccessBody Mass Index and Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer
Author(s) -
Giuseppe Floris,
François Richard,
Anne-Sophie Hamy,
Lynn Jongen,
Hans Wildiers,
Jan Ardui,
Kevin Punie,
Ann Smeets,
Patrick Berteloot,
Ignace Vergote,
Diane De Croze,
Didier Meseure,
Anne VincentSalomon,
Marick Laé,
Fabien Reyal,
Elia Biganzoli,
Patrick Neven,
Christine Desmedt
Publication year - 2020
Publication title -
journal of the national cancer institute
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.797
H-Index - 356
eISSN - 1460-2105
pISSN - 0027-8874
DOI - 10.1093/jnci/djaa090
Subject(s) - medicine , hazard ratio , overweight , body mass index , breast cancer , odds ratio , confidence interval , oncology , triple negative breast cancer , lean body mass , chemotherapy , proportional hazards model , gastroenterology , cancer , body weight
High levels of stromal tumor-infiltrating lymphocytes (sTIL) are associated with increased pathological complete response (pCR) rate and longer survival after neoadjuvant chemotherapy in triple-negative breast cancer (TNBC) patients. Here, we evaluated the value of sTIL in predicting pCR and explored prognosis in TNBC patients treated with neoadjuvant chemotherapy according to body mass index (BMI).