Open AccessSevere Neurological Sequelae after a Recreational Dose of LSD
Author(s) -
Rachel Aakerøy,
Wenche Rødseth Brede,
Stian Bergseng Stølen,
HegeMerete Krabseth,
Lisbeth Solem Michelsen,
Trygve Andreassen,
Tiina Ader,
Joachim Frost,
Grete Slettom,
Ole Martin Steihaug,
Lars Slørdal
Publication year - 2020
Publication title -
journal of analytical toxicology.
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.161
H-Index - 76
eISSN - 1945-2403
pISSN - 0146-4760
DOI - 10.1093/jat/bkaa145
Subject(s) - lysergic acid diethylamide , cardiorespiratory fitness , adverse effect , recreational use , medicine , serum concentration , cardiorespiratory arrest , physiology , pharmacology , recreation , anesthesia , receptor , biology , ecology , serotonin
A young man with an unremarkable medical history suffered a seizure with subsequent cardiorespiratory arrest and severe neurological sequelae after ingesting a blotter. Analysis of a similar blotter and a serum sample obtained 3 h after the event detected lysergic acid diethylamide (LSD) at an amount of 300 µg in the blotter and at a concentration of 4.0 ng/mL (12.4 nmol/L) in the serum. No other drugs were present in concentrations which may confer significant effects. In addition, no individual traits which would make the patient particularly susceptible to adverse LSD effects have subsequently been identified. This suggests that LSD may confer toxic effects in previously healthy individuals.