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Reducing dietary crude protein in early nursery has been suggested as a way to conquer the challenge of post-weaning diarrhea. In order to meet the amino acid requirement in RCP diets, feed grade amino acids are typically used, but the detrimental effect on growth performance associated with the aggressive usage of these amino acids resulted in the establishment of dietary limits. Given the fact that protein deposition rate is the highest in young pigs, lower amino acid consumption could slow the growth rate and feed efficiency in early nursery phase. Therefore, identifying feed additives that increase nutrient retention not only can further reduce dietary nitrogen but also maintain GI tract health. Among all feed additives that exert improvements on nutrient digestibility, peptide and organic acids will be discussed here. Peptide, a di- tri amino acid, is absorbed more efficiently than free amino acids in the small intestine through a peptide transporter at the enteric site. In addition, aside from meeting the amino acid requirement, the bioactive peptide possesses functions such as antimicrobial, antioxidant, anti-inflammatory, and as a stimulated Peptide transporter associated with nutrient absorption. Hence, a dietary peptide can help pigs meet the nutrient requirement in RCP diets. Organic acids, on the other hand, have been found to lower gastric pH which improves nutrient absorption, alters microbiome structure (via bacteriostatic and bactericidal) and promotes the growth and health of animals. In addition, organic acids are a ready energy source which is especially critical since nutrient supply disruption, due to low intake during early weaning, is commonly found in weaning pigs. It is noteworthy that variations of growth-promoting effects do exist for both peptide and organic acid products. Thus, understanding the mode of action and response of dietary peptide and organic acid supplements when used across different farm settings is important to help producers decide when to transfer to an antibiotic-free, low zinc operation.

105 Feed Additives That Optimize Nitrogen Bio-availability in Nursery Pigs Fed Reducing Crude Protein Diets