The Effects of Gamma Irradiation on Chemical Biomarker Recovery from Mixed Chemical/Biological Threat Exposure Specimens | Zendy

Samantha L. Isenberg | Zendy; Melissa D. Carter | Zendy; J Moon | Zendy; Sarah Laughlin | Zendy; Marla Petway | Zendy; Mike A. Mojica | Zendy; Julia E. Rood | Zendy; Alexis K. Gursky | Zendy; Cody I. Sheppard | Zendy; Dennis A. Bagarozzi | Zendy; James L. Pirkle | Zendy; Rudolph C. Johnson | Zendy

Open Access

The Effects of Gamma Irradiation on Chemical Biomarker Recovery from Mixed Chemical/Biological Threat Exposure Specimens

Author(s) -

Samantha L. Isenberg,

Melissa D. Carter,

J Moon,

Sarah Laughlin,

Marla Petway,

Mike A. Mojica,

Julia E. Rood,

Alexis K. Gursky,

Cody I. Sheppard,

Dennis A. Bagarozzi,

James L. Pirkle,

Rudolph C. Johnson

Publication year - 2020

Publication title -

the journal of applied laboratory medicine

Language(s) - English

Resource type - Journals

eISSN - 2576-9456

pISSN - 2475-7241

DOI - 10.1093/jalm/jfz022

Subject(s) - gamma irradiation , biomarker , irradiation , toxicology , chemistry , radiochemistry , biology , biochemistry , physics , nuclear physics

Irradiative sterilization of clinical specimens prior to chemical laboratory testing provides a way to not only sterilize pathogens and ensure laboratorian safety but also preserve sample volume and maintain compatibility with quantitative chemical diagnostic protocols. Since the compatibility of clinical biomarkers with gamma irradiation is not well characterized, a subset of diagnostic biomarkers ranging in molecular size, concentration, and clinical matrix was analyzed to determine recovery following gamma irradiation.

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