Open AccessObservational Study of Receptor Binding Domain Spike Antibody Responses to 3 SARS-CoV-2 Vaccinations in Noninfected Subjects: Parallel Neutralizing Antibody and Cardiac Troponin I and T Observations
Author(s) -
Fred S. Apple,
Bryan Bothwell,
Jaya Koti,
Westley Bauer,
Robert Dwyer,
Haode Chen,
Hao Wu,
Pu Li,
Britanny Lindgren,
Sydney Gottlieb,
Brynn Okeson,
Karen Schulz
Publication year - 2022
Publication title -
the journal of applied laboratory medicine
Language(s) - English
Resource type - Journals
eISSN - 2576-9456
pISSN - 2475-7241
DOI - 10.1093/jalm/jfac053
Subject(s) - medicine , vaccination , antibody , troponin i , virology , immunology , myocardial infarction
Our goals were to demonstrate receptor binding domain spike 1 (RBD S1) protein antibody (Ab) kinetic responses to multiple vaccines over approximately 180 days, neutralizing Ab effectiveness, and high-sensitivity cardiac troponin I (hs-cTnI) and T (hs-cTnT) responses in postvaccinated, non-SARS-CoV-2-infected subjects.