Open AccessA mutation in the glycosyltransferase gene lafB causes daptomycin hypersusceptibility in Enterococcus faecium
Author(s) -
Sarita V. Mello,
Daria Van Tyne,
François Lebreton,
Simone Q Silva,
Mara Corrêa Lelles Nogueira,
Michael S. Gilmore,
Ilana Lopes Baratella da Cunha Camargo
Publication year - 2019
Publication title -
the journal of antimicrobial chemotherapy/journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkz403
Subject(s) - daptomycin , enterococcus faecium , biology , microbiology and biotechnology , gene , enterococcus , complementation , genetics , phenotype , bacteria , antibiotics , vancomycin , staphylococcus aureus
To verify dissemination of daptomycin-non-susceptible Enterococcus faecium in a hospital where daptomycin was not in use and to understand the evolutionary pathways connecting daptomycin hypersusceptibility to non-susceptibility.