Impact of a diagnostics-driven antifungal stewardship programme in a UK tertiary referral teaching hospital
Author(s) -
Riina RautemaaRichardson,
Vilma Rautemaa,
F Al-Wathiqi,
CB Moore,
Linda Craig,
Tim Felton,
Eavan G. Muldoon
Publication year - 2018
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dky360
Subject(s) - micafungin , medicine , guideline , antifungal , invasive candidiasis , intensive care medicine , intensive care unit , amphotericin b , fluconazole , pathology , dermatology
A concise invasive candidosis guideline (based on the ESCMID candidaemia guideline) utilizing an informative biomarker [serum β-1-3-d-glucan (BDG)] was developed in 2013 by an antifungal stewardship (AFS) team and implemented with the help of an AFS champion in 2014. The main aims of the AFS programme were to reduce inappropriate use of antifungals and improve patient outcomes. The aim of this project was to evaluate the compliance of the ICU teams with the invasive candidosis guideline and the impact of the AFS programme on mortality and antifungal consumption on the ICUs (total of 71 beds).
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