Seeking an optimal dosing regimen for OZ439/DSM265 combination therapy for treating uncomplicated falciparum malaria | Zendy

S Dini | Zendy; Sophie Zaloumis | Zendy; David J. Price | Zendy; Nathalie Gobeau | Zendy; Anne Kümmel | Zendy; Mohammed Cherkaoui | Zendy; Joerg J. Moehrle | Zendy; James McCarthy | Zendy; J. A. Simpson | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Seeking an optimal dosing regimen for OZ439/DSM265 combination therapy for treating uncomplicated falciparum malaria

Author(s) -

S Dini,

Sophie Zaloumis,

David J. Price,

Nathalie Gobeau,

Anne Kümmel,

Mohammed Cherkaoui,

Joerg J. Moehrle,

James McCarthy,

J. A. Simpson

Publication year - 2021

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkab181

Subject(s) - malaria , combination therapy , dosing , medicine , artemisinin , plasmodium falciparum , regimen , pharmacodynamics , pharmacology , dihydroartemisinin , intensive care medicine , immunology , pharmacokinetics

The efficacy of artemisinin-based combination therapies (ACTs), the first-line treatments for uncomplicated falciparum malaria, has been declining in malaria-endemic countries due to the emergence of malaria parasites resistant to these compounds. Novel alternative therapies are needed urgently to prevent the likely surge in morbidity and mortality due to failing ACTs.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research