
Apramycin resistance in epidemic carbapenem-resistant Klebsiella pneumoniae ST258 strains
Author(s) -
Ming C. Hao,
Jessica A. Schuyler,
Haifang Zhang,
Elena Shashkina,
Hong Du,
Derrick E. Fouts,
Michael J. Satlin,
Barry N. Kreiswirth,
Liang Chen
Publication year - 2021
Publication title -
the journal of antimicrobial chemotherapy/journal of antimicrobial chemotherapy
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkab131
Subject(s) - klebsiella pneumoniae , microbiology and biotechnology , plasmid , multilocus sequence typing , broth microdilution , antibiotic resistance , biology , antibiotics , escherichia coli , gene , genotype , minimum inhibitory concentration , genetics
Recent studies indicated that the monosubstituted deoxystreptamine aminoglycoside apramycin is a potent antibiotic against a wide range of MDR Gram-negative pathogens.