ReducedTrypanosoma cruzi-specific humoral response and enhanced T cell immunity after treatment interruption with benznidazole in chronic Chagas disease | Zendy

Melisa D. Castro Eiro | Zendy; María A. Natale | Zendy; M Alvarez | Zendy; Huifeng Shen | Zendy; Rodolfo Viotti | Zendy; Bruno Lococo | Zendy; Jacqueline Búa | Zendy; Myriam Núñez | Zendy; Graciela Bertocchi | Zendy; María C. Albareda | Zendy; Gonzalo César | Zendy; Rick L. Tarleton | Zendy; Susana A. Laucella | Zendy

Open Access

ReducedTrypanosoma cruzi-specific humoral response and enhanced T cell immunity after treatment interruption with benznidazole in chronic Chagas disease

Author(s) -

Melisa D. Castro Eiro,

María A. Natale,

M Alvarez,

Huifeng Shen,

Rodolfo Viotti,

Bruno Lococo,

Jacqueline Búa,

Myriam Núñez,

Graciela Bertocchi,

María C. Albareda,

Gonzalo César,

Rick L. Tarleton,

Susana A. Laucella

Publication year - 2021

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkab054

Subject(s) - benznidazole , chagas disease , trypanosoma cruzi , immunology , regimen , medicine , antibody , cd8 , cellular immunity , immune system , parasite hosting , world wide web , computer science

Interruption of benznidazole therapy due to the appearance of adverse effects, which is presumed to lead to treatment failure, is a major drawback in the treatment of chronic Chagas disease.

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