Open AccessSystematic review of mutations associated with resistance to the new and repurposedMycobacterium tuberculosisdrugs bedaquiline, clofazimine, linezolid, delamanid and pretomanid
Author(s) -
Suha Kadura,
N.S.P. King,
Maria Nakhoul,
Hongya Zhu,
Grant Theron,
Claudio U. Köser,
Farhat Mustafa
Publication year - 2020
Publication title -
the journal of antimicrobial chemotherapy/journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkaa136
Subject(s) - bedaquiline , clofazimine , linezolid , mycobacterium tuberculosis , drug resistance , tuberculosis , biology , resistance mutation , genetics , medicine , gene , polymerase chain reaction , reverse transcriptase , vancomycin , bacteria , immunology , leprosy , pathology , staphylococcus aureus
Improved genetic understanding of Mycobacterium tuberculosis (MTB) resistance to novel and repurposed anti-tubercular agents can aid the development of rapid molecular diagnostics.