Open AccessBaloxavir Marboxil Treatment of Nude Mice Infected With Influenza A Virus
Author(s) -
Maki Kiso,
Seiya Yamayoshi,
Jurika Murakami,
Yoshihiro Kawaoka
Publication year - 2019
Publication title -
the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiz665
Subject(s) - virus , neuraminidase , virology , neuraminidase inhibitor , respiratory tract , influenza a virus , respiratory system , biology , mutant , orthomyxoviridae , medicine , immunology , covid-19 , infectious disease (medical specialty) , biochemistry , disease , gene
Immunocompromised patients infected with influenza virus require prolonged treatment with neuraminidase inhibitors, because these patients are not able to eradicate the virus from the respiratory tract, leading to the emergence of drug-resistant mutant viruses.