Open AccessHuman Immunodeficiency Virus Exposure but Not Early Cytomegalovirus Infection Is Associated With Increased Hospitalization and Decreased Memory T-Cell Responses to Tetanus Vaccine
Author(s) -
Christiana Smith,
Natasha O. Moraka,
Maryanne Ibrahim,
Sikhulile Moyo,
Gloria Mayondi,
Betsy Kammerer,
Jean Leidner,
Simani Gaseitsiwe,
Shaobing Li,
Roger Shapiro,
Shahin Lockman,
Adriana Weinberg
Publication year - 2019
Publication title -
the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiz590
Subject(s) - tetanus , toxoid , immunology , medicine , cytomegalovirus , virology , vaccination , virus , viral disease , herpesviridae
Human immunodeficiency virus (HIV)-exposed, uninfected (HEU) infants experience high rates of infectious morbidity. We hypothesized that early cytomegalovirus (CMV) infection was associated with increased hospitalization rates and decreased vaccine responses in HEU compared with HIV-unexposed (HUU) infants.