Open AccessHuman Immunodeficiency Virus Infection Is Associated With Preterm Delivery Independent of Vaginal Microbiota in Pregnant African Women
Author(s) -
Muchaneta Gudza-Mugabe,
Enock Havyarimana,
Shameem Z. Jaumdally,
Kirsty Lee Garson,
Katie Lennard,
Andrew Tarupiwa,
Fortunate Mugabe,
Tarisai Marere,
Rooyen T. Mavenyengwa,
Lindi Masson,
Heather B. Jaspan
Publication year - 2019
Publication title -
the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiz584
Subject(s) - pregnancy , medicine , bacterial vaginosis , gestation , vagina , immunology , obstetrics , vaginal delivery , human immunodeficiency virus (hiv) , gestational age , biology , genetics , surgery
During pregnancy, the vaginal microbiota is relatively stable. However, African women have more diverse vaginal microbiota than their European counterparts, in addition to high human immunodeficiency virus (HIV) prevalence and risk of adverse birth outcomes. Although HIV is associated with alterations in vaginal microbiota and inflammation in nonpregnant women, these relationships are underexplored in pregnant women.