Zika Virus Causes Acute and Chronic Prostatitis in Mice and Macaques | Zendy

Jacques Halabi | Zendy; Brett W. Jagger | Zendy; Vanessa Salazar | Zendy; Emma S. Winkler | Zendy; James P. White | Zendy; Peter A. Humphrey | Zendy; Alec J. Hirsch | Zendy; Daniel N. Streblow | Zendy; Michael Diamond | Zendy; Kelle H. Moley | Zendy

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Zika Virus Causes Acute and Chronic Prostatitis in Mice and Macaques

Author(s) -

Jacques Halabi,

Brett W. Jagger,

Vanessa Salazar,

Emma S. Winkler,

James P. White,

Peter A. Humphrey,

Alec J. Hirsch,

Daniel N. Streblow,

Michael Diamond,

Kelle H. Moley

Publication year - 2019

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jiz533

Subject(s) - prostatitis , zika virus , prostate , epididymis , virus , sexual transmission , infertility , male infertility , immunology , medicine , biology , virology , sperm , pregnancy , andrology , microbicide , cancer , human immunodeficiency virus (hiv) , genetics

Sexual transmission and persistence of Zika virus (ZIKV) in the male reproductive tract has raised concerned for potential damaging effects on function. Animal studies have demonstrated that ZIKV virus can infect and damage the testis and epididymis, and these results has been correlated to lower sperm counts in ZIKV-infected humans. The prostate plays a vital role in the male reproductive tract, with acute and chronic prostatitis linked to male infertility.

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