Precision Medicine and Precision Public Health in the Era of Pathogen Next-Generation Sequencing | Zendy

Mariana Leguía | Zendy; Antón VilaSanjurjo | Zendy; Patrick Chain | Zendy; Irina Maljkovic Berry | Zendy; Richard G. Jarman | Zendy; Simon Pollett | Zendy

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Precision Medicine and Precision Public Health in the Era of Pathogen Next-Generation Sequencing

Author(s) -

Mariana Leguía,

Antón VilaSanjurjo,

Patrick Chain,

Irina Maljkovic Berry,

Richard G. Jarman,

Simon Pollett

Publication year - 2019

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jiz424

Subject(s) - infectious disease (medical specialty) , public health , context (archaeology) , precision medicine , dna sequencing , genomics , data science , engineering ethics , computational biology , medicine , biology , disease , computer science , engineering , genome , genetics , pathology , dna , paleontology , gene

This brief report serves as an introduction to a supplement of the Journal of Infectious Diseases entitled "Next-Generation Sequencing (NGS) Technologies to Advance Global Infectious Disease Research." We briefly discuss the history of NGS technologies and describe how the techniques developed during the past 40 years have impacted our understanding of infectious diseases. Our focus is on the application of NGS in the context of pathogen genomics. Beyond obvious clinical and public health applications, we also discuss the challenges that still remain within this rapidly evolving field.

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