Open AccessPrecision Medicine and Precision Public Health in the Era of Pathogen Next-Generation Sequencing
Author(s) -
Mariana Leguía,
Antón Vila-Sanjurjo,
Patrick Chain,
Irina Maljkovic Berry,
Richard G. Jarman,
Simon Pollett
Publication year - 2019
Publication title -
the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiz424
Subject(s) - infectious disease (medical specialty) , public health , genomics , data science , context (archaeology) , precision medicine , dna sequencing , computational biology , engineering ethics , biology , medicine , disease , computer science , genome , genetics , engineering , pathology , dna , paleontology , gene
This brief report serves as an introduction to a supplement of the Journal of Infectious Diseases entitled "Next-Generation Sequencing (NGS) Technologies to Advance Global Infectious Disease Research." We briefly discuss the history of NGS technologies and describe how the techniques developed during the past 40 years have impacted our understanding of infectious diseases. Our focus is on the application of NGS in the context of pathogen genomics. Beyond obvious clinical and public health applications, we also discuss the challenges that still remain within this rapidly evolving field.