Open AccessInduction and Kinetics of Complement-Fixing Antibodies Against Plasmodium vivax Merozoite Surface Protein 3α and Relationship With Immunoglobulin G Subclasses and Immunoglobulin M
Author(s) -
Damian Oyong,
Danny W. Wilson,
Bridget E. Barber,
Timothy William,
Jianlin Jiang,
Mary R. Galinski,
Freya J. I. Fowkes,
Matthew J. Grigg,
James G. Beeson,
Nicholas M. Anstey,
Michelle J. Boyle
Publication year - 2019
Publication title -
the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiz407
Subject(s) - plasmodium vivax , antibody , complement fixation test , immunoglobulin g , virology , biology , immunoglobulin m , immunology , malaria , plasmodium falciparum , serology
Complement-fixing antibodies are important mediators of protection against Plasmodium falciparum malaria. However, complement-fixing antibodies remain uncharacterized for Plasmodium vivax malaria. P. vivax merozoite surface protein 3α (PvMSP3α) is a target of acquired immunity and a potential vaccine candidate.