Open AccessImpact of Herpes Simplex Virus Type 2 and Human Immunodeficiency Virus Dual Infection on Female Genital Tract Mucosal Immunity and the Vaginal Microbiome
Author(s) -
Marla J. Keller,
Ashley Huber,
Lilia Espinoza,
Myrna G. Serrano,
Hardik I. Parikh,
Gregory A. Buck,
Jeremy A W Gold,
Yiqun Wu,
Tao Wang,
Betsy C. Herold
Publication year - 2019
Publication title -
the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiz203
Subject(s) - immunology , herpes simplex virus , biology , vagina , virus , immunity , immune system , virology , outbreak , medicine , genetics
Mechanisms linking herpes simplex virus type 2 (HSV-2) with human immunodeficiency virus (HIV) are not fully defined. We tested the hypothesis that HSV-2 and HIV dual infection is associated with cervicovaginal inflammation and/or vaginal dysbiosis.