Open AccessPoliovirus Type 2 Seroprevalence Following Full- or Fractional-Dose Inactivated Poliovirus Vaccine in the Period After Sabin Type 2 Withdrawal in Sri Lanka
Author(s) -
Deepa Gamage,
Ondrej Mach,
Samitha Ginige,
William C. Weldon,
M. Steven Oberste,
Visalakshi Jeyaseelan,
Roland W. Sutter
Publication year - 2019
Publication title -
the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiz026
Subject(s) - inactivated poliovirus vaccine , seroprevalence , poliovirus , medicine , virology , immunization , antibody , titer , poliomyelitis , neutralizing antibody , antibody titer , immunology , virus , serology
In July 2016, Sri Lanka replaced 1 intramuscular dose of inactivated poliovirus vaccine (IPV) with 2 doses of intradermal fractional-dose IPV (fIPV) in its routine immunization schedule. We carried out a survey of seroprevalence of antipolio antibodies in children who received 2 fIPV doses and compared it with those who received 1 full IPV dose.