Artemisinin Resistance and Stage Dependency of Parasite Clearance in Falciparum Malaria | Zendy

Benjamas Intharabut | Zendy; Hugh Kingston | Zendy; Ketsanee Srinamon | Zendy; Elizabeth A. Ashley | Zendy; Mallika Imwong | Zendy; Mehul Dhorda | Zendy; Charles J. Woodrow | Zendy; Kasia Stepniewska | Zendy; Kamolrat Silamut | Zendy; Nicholas Day | Zendy; Arjen M. Dondorp | Zendy; Nicholas J. White | Zendy

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Artemisinin Resistance and Stage Dependency of Parasite Clearance in Falciparum Malaria

Author(s) -

Benjamas Intharabut,

Hugh Kingston,

Ketsanee Srinamon,

Elizabeth A. Ashley,

Mallika Imwong,

Mehul Dhorda,

Charles J. Woodrow,

Kasia Stepniewska,

Kamolrat Silamut,

Nicholas Day,

Arjen M. Dondorp,

Nicholas J. White

Publication year - 2018

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jiy673

Subject(s) - artemisinin , malaria , plasmodium falciparum , parasite hosting , dependency (uml) , biology , drug resistance , resistance (ecology) , virology , traditional medicine , medicine , immunology , microbiology and biotechnology , ecology , computer science , world wide web , software engineering

Artemisinin resistance in falciparum malaria is associated with kelch13 propeller mutations, reduced ring stage parasite killing, and, consequently, slow parasite clearance. We assessed how parasite age affects parasite clearance in artemisinin resistance.

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