Pregnant Women Have Attenuated Innate Interferon Responses to 2009 Pandemic Influenza A Virus Subtype H1N1 | Zendy

Rebecca L. Forbes | Zendy; Peter Wark | Zendy; Vanessa E. Murphy | Zendy; Peter G. Gibson | Zendy

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Pregnant Women Have Attenuated Innate Interferon Responses to 2009 Pandemic Influenza A Virus Subtype H1N1

Author(s) -

Rebecca L. Forbes,

Peter Wark,

Vanessa E. Murphy,

Peter G. Gibson

Publication year - 2012

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jis377

Subject(s) - vaccination , peripheral blood mononuclear cell , medicine , immunology , virus , interferon , pregnancy , immunity , virology , influenza a virus , innate immune system , pandemic , immune system , biology , disease , infectious disease (medical specialty) , biochemistry , genetics , covid-19 , in vitro

Pregnant women are considered to have a high risk for influenza virus infection, although little is known about the biological reasons for this risk. Antiviral immunity is critical during influenza virus infection, and understanding the changes that occur during pregnancy and the effect of vaccination is essential for improving health outcomes for mother and baby.

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