Omicron Breakthrough Infection After Heterologous Prime-Boost Vaccination Induces a Vigorous Antibody Response
Author(s) -
Augusto Varese,
Bianca Mazzitelli,
Fernando Erra Díaz,
María Victoria Kjolhede,
Diego Ojeda,
Alejandra Vellicce,
Penélope Arto,
Carla Y Cícero,
María Pascowsky,
Laura Figueras,
Bárbara Broese,
Rosa Dávila,
Rocío Zarlenga,
Federico Rivelli,
Camila Verruno,
Valeria Silenzi,
Ivana Beltrán,
Andrea V. Gamarnik,
Ana Ceballos,
Carlos Zala,
Adelina Badolati,
Jorge Geffner
Publication year - 2022
Publication title -
the journal of infectious diseases
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiac250
Subject(s) - vaccination , asymptomatic , neutralizing antibody , antibody , heterologous , antibody response , virology , immunology , medicine , biology , pathology , biochemistry , gene
Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant is usually asymptomatic or mild and appears to be poorly immunogenic at least in unvaccinated individuals. Here, we found that health care workers vaccinated with 2 doses of Sputnik V and a booster dose of ChAdOx1 mount a vigorous neutralizing-antibody response after Omicron breakthrough infection.
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