Open AccessImpaired T-Lymphocyte Responses During Childhood Staphylococcus aureus Infection
Author(s) -
Zhaotao Li,
Pavani Beesetty,
George Gerges,
Maureen Kleinhenz,
Melissa MooreClingenpeel,
Ching Yang,
Luul B Ahmed,
Josey Hensley,
Lisa Steele,
Anita S. Chong,
Christopher P. Montgomery
Publication year - 2021
Publication title -
the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiab326
Subject(s) - staphylococcus aureus , immunology , microbiology and biotechnology , lymphocyte , staphylococcal infections , medicine , biology , bacteria , genetics
Staphylococcus aureus infections are common throughout the lifespan, with recurrent infections occurring in nearly half of infected children. There is no licensed vaccine, underscoring the need to better understand how S. aureus evades protective immunity. Despite much study, the relative contributions of antibodies and T cells to protection against S. aureus infections in humans are not fully understood.