Time-Varying Association Between Severe Respiratory Syncytial Virus Infections and Subsequent Severe Asthma and Wheeze and Influences of Age at the Infection | Zendy

Xin Wang | Zendy; You Li | Zendy; Harish Nair | Zendy; Harry Campbell | Zendy; Rachel M Reeves | Zendy; Maarten van Wijhe | Zendy; Thea Kølsen Fischer | Zendy; Lone Simonsen | Zendy; Ramona Trebbien | Zendy; Sabine Tong | Zendy; Mathieu Bangert | Zendy; Clarisse Demont | Zendy; Toni Lehtonen | Zendy; Turku University Hospital | Zendy; Terho Heikkinen | Zendy; Anne Teirlinck | Zendy; Michiel van Boven | Zendy; Wim van der Hoek | Zendy; Nicoline van der Maas | Zendy; Adam Meijer | Zendy; Liliana Vázquez Fernández | Zendy; Håkon Bøas | Zendy; Terese Bekkevold | Zendy; Elmira Flem | Zendy; Luca Stona | Zendy; Irene Speltra | Zendy; Carlo Giaquinto | Zendy; Arnaud Chéret | Zendy; Amanda Leach | Zendy; Sonia Stoszek | Zendy; Philippe Beutels | Zendy; Louis Bont | Zendy; Andrew J. Pollard | Zendy; Peter Openshaw | Zendy; Michael E. Abram | Zendy; Kena A. Swanson | Zendy; Brian Rosen | Zendy; Eva Molero | Zendy

Open Access

Time-Varying Association Between Severe Respiratory Syncytial Virus Infections and Subsequent Severe Asthma and Wheeze and Influences of Age at the Infection

Author(s) -

Xin Wang,

You Li,

Harish Nair,

Harry Campbell,

Rachel M Reeves,

Maarten van Wijhe,

Thea Kølsen Fischer,

Lone Simonsen,

Ramona Trebbien,

Sabine Tong,

Mathieu Bangert,

Clarisse Demont,

Toni Lehtonen,

Turku University Hospital,

Terho Heikkinen,

Anne Teirlinck,

Michiel van Boven,

Wim van der Hoek,

Nicoline van der Maas,

Adam Meijer,

Liliana Vázquez Fernández,

Håkon Bøas,

Terese Bekkevold,

Elmira Flem,

Luca Stona,

Irene Speltra,

Carlo Giaquinto,

Arnaud Chéret,

Amanda Leach,

Sonia Stoszek,

Philippe Beutels,

Louis Bont,

Andrew J. Pollard,

Peter Openshaw,

Michael E. Abram,

Kena A. Swanson,

Brian Rosen,

Eva Molero

Publication year - 2021

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jiab308

Subject(s) - wheeze , medicine , asthma , pediatrics , confidence interval , hazard ratio , cohort , respiratory tract infections , proportional hazards model , cohort study , lower respiratory tract infection , respiratory sounds , respiratory system

Early-life severe respiratory syncytial virus (RSV) infection has been associated with subsequent risk of asthma and recurrent wheeze. However, changes in the association over time and the interaction effect of the age at first RSV infection are less well understood. We aimed to assess the time-varying association between RSV and subsequent asthma and wheeze admission and explore how the association was affected by the age at RSV infection.

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