Open AccessImpact of 13-Valent Pneumococcal Conjugate Vaccine on Nasopharyngeal Carriage Rates of Streptococcus pneumoniae in a Rural Community in the Dominican Republic
Author(s) -
Michelle Dunn,
Fernanda C. Lessa,
Jacqueline Sánchez,
Ramona Cordero,
Jesús Feris-Iglesias,
Doraliza Cedano,
Maria da Glória Carvalho,
Josefina Fernández,
Kristen A. Feemster
Publication year - 2021
Publication title -
the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiab172
Subject(s) - pneumococcal conjugate vaccine , medicine , streptococcus pneumoniae , vaccination , carriage , pneumococcal infections , pediatrics , confidence interval , cohort , odds ratio , immunology , antibiotics , biology , pathology , microbiology and biotechnology
Invasive pneumococcal disease (IPD) leads to thousands of pediatric deaths annually. Pneumococcal colonization precedes IPD. In 2013, the Dominican Republic introduced the 13-valent pneumococcal conjugate vaccine (PCV13) into its routine infant immunization program, with doses at ages 2, 4, and 12 months. Prevalence of pneumococcal nasopharyngeal colonization was evaluated post-PCV13 introduction.