Hemolytic Membrane Vesicles of Group B Streptococcus Promote Infection | Zendy

Blair Armistead | Zendy; Phoenicia Quach | Zendy; Jessica M. Snyder | Zendy; Verónica Santana-Ufret | Zendy; Anna Furuta | Zendy; Alyssa Brokaw | Zendy; Lakshmi Rajagopal | Zendy

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Hemolytic Membrane Vesicles of Group B Streptococcus Promote Infection

Author(s) -

Blair Armistead,

Phoenicia Quach,

Jessica M. Snyder,

Verónica Santana-Ufret,

Anna Furuta,

Alyssa Brokaw,

Lakshmi Rajagopal

Publication year - 2020

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jiaa548

Subject(s) - virulence , cytolysin , streptococcus agalactiae , virulence factor , microbiology and biotechnology , hemolysin , biology , group b , streptococcus , pathogenesis , group a , bacterial outer membrane , immunology , bacteria , medicine , escherichia coli , gene , biochemistry , genetics

Group B streptococci (GBS) are β-hemolytic, Gram-positive bacteria associated with fetal injury, preterm birth, spontaneous abortion, and neonatal infections. A key factor promoting GBS virulence is the β-hemolysin/cytolysin, a pigmented ornithine rhamnolipid (also known as granadaene) associated with the bacterial surface.

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