Open AccessHemolytic Membrane Vesicles of Group B Streptococcus Promote Infection
Author(s) -
Blair Armistead,
Phoenicia Quach,
Jessica M. Snyder,
Verónica Santana-Ufret,
Anna Furuta,
Alyssa Brokaw,
Lakshmi Rajagopal
Publication year - 2020
Publication title -
the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiaa548
Subject(s) - virulence , cytolysin , streptococcus agalactiae , virulence factor , microbiology and biotechnology , hemolysin , biology , group b , streptococcus , pathogenesis , group a , bacterial outer membrane , immunology , bacteria , medicine , escherichia coli , gene , biochemistry , genetics
Group B streptococci (GBS) are β-hemolytic, Gram-positive bacteria associated with fetal injury, preterm birth, spontaneous abortion, and neonatal infections. A key factor promoting GBS virulence is the β-hemolysin/cytolysin, a pigmented ornithine rhamnolipid (also known as granadaene) associated with the bacterial surface.