Primary and Secondary Dengue Virus Infections Elicit Similar Memory B-Cell Responses, but Breadth to Other Serotypes and Cross-Reactivity to Zika Virus Is Higher in Secondary Dengue | Zendy

Paulina Andrade | Zendy; Parnal Narvekar | Zendy; Magelda Montoya | Zendy; Daniela Michlmayr | Zendy; Ángel Balmaseda | Zendy; Joséfina Coloma | Zendy; Eva Harris | Zendy

Open Access

Primary and Secondary Dengue Virus Infections Elicit Similar Memory B-Cell Responses, but Breadth to Other Serotypes and Cross-Reactivity to Zika Virus Is Higher in Secondary Dengue

Author(s) -

Paulina Andrade,

Parnal Narvekar,

Magelda Montoya,

Daniela Michlmayr,

Ángel Balmaseda,

Joséfina Coloma,

Eva Harris

Publication year - 2020

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1093/infdis/jiaa120

Subject(s) - dengue virus , dengue fever , zika virus , serotype , virology , biology , virus , flavivirus , immunology

The 4 antigenically distinct serotypes of dengue virus (DENV) share extensive homology with each other and with the closely related Zika flavivirus (ZIKV). The development of polyclonal memory B cells (MBCs) to the 4 DENV serotypes and ZIKV during DENV infection is not fully understood.

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