Open AccessT Lymphocyte Subsets Associated With Prevalent Diabetes in Veterans With and Without Human Immunodeficiency Virus
Author(s) -
Samuel Bailin,
Kathleen McGinnis,
Wyatt J. McDonnell,
Kaku SoArmah,
Melissa Wellons,
Russell P. Tracy,
Margaret F. Doyle,
S. Mallal,
Amy C. Justice,
Matthew S. Freiberg,
Alan Landay,
Celestine N. Wanjalla,
John R. Koethe
Publication year - 2020
Publication title -
the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1093/infdis/jiaa069
Subject(s) - cd38 , diabetes mellitus , serostatus , medicine , immunology , cd8 , population , immunosenescence , immune system , logistic regression , t cell , viral load , human immunodeficiency virus (hiv) , endocrinology , biology , environmental health , genetics , stem cell , cd34
A higher proportion of circulating memory CD4+ T cells is associated with prevalent diabetes mellitus in the general population. Given the broad changes in adaptive immunity, including memory T-cell expansion, and rising prevalence of diabetes in the human immunodeficiency virus (HIV) population, we assessed whether similar relationships were present in persons with HIV (PWH).