Phosphorylation of GluA1-Ser831 by CaMKII Activation in the Caudate and Putamen Is Required for Behavioral Sensitization After Challenge Nicotine in Rats | Zendy

Sunghyun Kim | Zendy; Sumin Sohn | Zendy; Eun Sang Choe | Zendy

Open Access

Phosphorylation of GluA1-Ser831 by CaMKII Activation in the Caudate and Putamen Is Required for Behavioral Sensitization After Challenge Nicotine in Rats

Author(s) -

Sunghyun Kim,

Sumin Sohn,

Eun Sang Choe

Publication year - 2022

Publication title -

the international journal of neuropsychopharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.897

H-Index - 107

eISSN - 1469-5111

pISSN - 1461-1457

DOI - 10.1093/ijnp/pyac034

Subject(s) - medium spiny neuron , nicotine , ampa receptor , pharmacology , metabotropic glutamate receptor 5 , chemistry , sensitization , metabotropic glutamate receptor 1 , nmda receptor , glutamate receptor , dopamine , metabotropic glutamate receptor , medicine , endocrinology , neuroscience , receptor , biology , striatum , biochemistry

Phosphorylation of the glutamate receptor (GluA1) subunit of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor plays a crucial role in behavioral sensitization after exposure to psychostimulants. The present study determined the potential role of serine 831 (Ser831) phosphorylation in the GluA1 subunit of the caudate and putamen (CPu) in behavioral sensitization after challenge nicotine.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research