Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk, in the Breast Cancer Association Consortium | Zendy

Pooja Middha | Zendy; Sara Lindström | Zendy; Sabine Behrens | Zendy; Xiaoliang Wang | Zendy; Kyriaki Michailidou | Zendy; Manjeet K. Bolla | Zendy; Qin Wang | Zendy; Joe Dennis | Zendy; Alison M. Dunning | Zendy; Paul D.P. Pharoah | Zendy; Marjanka K. Schmidt | Zendy; Peter Kraft | Zendy; Montserrat GarcíaClosas | Zendy; Douglas F. Easton | Zendy; Roger L. Milne | Zendy; Jenny ChangClaude | Zendy

Open Access

Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk, in the Breast Cancer Association Consortium

Author(s) -

Pooja Middha,

Sara Lindström,

Sabine Behrens,

Xiaoliang Wang,

Kyriaki Michailidou,

Manjeet K. Bolla,

Qin Wang,

Joe Dennis,

Alison M. Dunning,

Paul D.P. Pharoah,

Marjanka K. Schmidt,

Peter Kraft,

Montserrat GarcíaClosas,

Douglas F. Easton,

Roger L. Milne,

Jenny ChangClaude

Publication year - 2019

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyz193

Subject(s) - breast cancer , odds ratio , oncology , medicine , snp , cancer , single nucleotide polymorphism , logistic regression , estrogen receptor , case control study , genotype , biology , genetics , gene

Previous gene-environment interaction studies of breast cancer risk have provided sparse evidence of interactions. Using the largest available dataset to date, we performed a comprehensive assessment of potential effect modification of 205 common susceptibility variants by 13 established breast cancer risk factors, including replication of previously reported interactions.

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