Open AccessGlobal birth prevalence of congenital heart defects 1970–2017: updated systematic review and meta-analysis of 260 studies
Author(s) -
Yingjuan Liu,
Sen Chen,
Liesl Zühlke,
Graeme C M Black,
Mun-Kit Choy,
Ningxiu Li,
Bernard Keavney
Publication year - 2019
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dyz009
Subject(s) - medicine , confidence interval , meta analysis , ductus arteriosus , heart disease , pediatrics , epidemiology , relative risk , demography , cardiology , sociology
Globally, access to healthcare and diagnostic technologies are known to substantially impact the reported birth prevalence of congenital heart disease (CHD). Previous studies have shown marked heterogeneity between different regions, with a suggestion that CHD prevalence is rising globally, but the degree to which this reflects differences due to environmental or genetic risk factors, as opposed to improved detection, is uncertain. We performed an updated systematic review to address these issues.