Reproducibility of telomere length assessment: an international collaborative study
Author(s) -
Carmen MartinRuiz,
Duncan M. Baird,
Lauréline Roger,
Petra Boukamp,
Damir Krunic,
Richard Cawthon,
Martin M. Dokter,
Pim van der Harst,
Sofie Bekaert,
Tim De Meyer,
Göran Roos,
Ulrika Svenson,
Veryan Codd,
Nilesh J. Samani,
Liane M. McGlynn,
Paul G. Shiels,
Karen A. Pooley,
Alison M. Dunning,
Rachel Cooper,
Andrew Wong,
Andrew Kingston,
Thomas von Zglinicki
Publication year - 2014
Publication title -
international journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.406
H-Index - 208
eISSN - 1464-3685
pISSN - 0300-5771
DOI - 10.1093/ije/dyu191
Subject(s) - telomere , reproducibility , coefficient of variation , pooling , biology , statistics , computational biology , computer science , mathematics , genetics , dna , artificial intelligence
Telomere length is a putative biomarker of ageing, morbidity and mortality. Its application is hampered by lack of widely applicable reference ranges and uncertainty regarding the present limits of measurement reproducibility within and between laboratories.
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