Is disrupted sleep a risk factor for Alzheimer’s disease? Evidence from a two-sample Mendelian randomization analysis | Zendy

Emma L. Anderson | Zendy; Rebecca C. Richmond | Zendy; Samuel E. Jones | Zendy; Gibran Hemani | Zendy; Kaitlin H. Wade | Zendy; Hassan S. Dashti | Zendy; Jacqueline M. Lane | Zendy; Heming Wang | Zendy; Richa Saxena | Zendy; Ben Brumpton | Zendy; Roxanna KorologouLinden | Zendy; Jonas B. Nielsen | Zendy; Bjørn Olav Åsvold | Zendy; Gonçalo R. Abecasis | Zendy; Elizabeth Coulthard | Zendy; Simon D. Kyle | Zendy; Robin N. Beaumont | Zendy; Jessica Tyrrell | Zendy; Timothy M. Frayling | Zendy; Marcus R. Munafò | Zendy; Andrew R. Wood | Zendy; Yoav BenShlomo | Zendy; Laura D. Howe | Zendy; Debbie A. Lawlor | Zendy; Michael N. Weedon | Zendy; George Davey Smith | Zendy

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Is disrupted sleep a risk factor for Alzheimer’s disease? Evidence from a two-sample Mendelian randomization analysis

Author(s) -

Emma L. Anderson,

Rebecca C. Richmond,

Samuel E. Jones,

Gibran Hemani,

Kaitlin H. Wade,

Hassan S. Dashti,

Jacqueline M. Lane,

Heming Wang,

Richa Saxena,

Ben Brumpton,

Roxanna KorologouLinden,

Jonas B. Nielsen,

Bjørn Olav Åsvold,

Gonçalo R. Abecasis,

Elizabeth Coulthard,

Simon D. Kyle,

Robin N. Beaumont,

Jessica Tyrrell,

Timothy M. Frayling,

Marcus R. Munafò,

Andrew R. Wood,

Yoav BenShlomo,

Laura D. Howe,

Debbie A. Lawlor,

Michael N. Weedon,

George Davey Smith

Publication year - 2020

Publication title -

international journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.406

H-Index - 208

eISSN - 1464-3685

pISSN - 0300-5771

DOI - 10.1093/ije/dyaa183

Subject(s) - mendelian randomization , alzheimer's disease , disease , risk factor , medicine , randomization , psychology , gerontology , randomized controlled trial , genetics , biology , gene , genotype , genetic variants

It is established that Alzheimer's disease (AD) patients experience sleep disruption. However, it remains unknown whether disruption in the quantity, quality or timing of sleep is a risk factor for the onset of AD.

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