Open AccessOncological outcomes of unsuspected pN2 in patients with non-small-cell lung cancer: a systematic review and meta-analysis
Author(s) -
Michiel A. Ijsseldijk,
Richard P. G. ten Broek,
Bastiaan Wiering,
Edo J. Hekma,
Marnix A.J. de Roos
Publication year - 2021
Publication title -
interactive cardiovascular and thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 56
eISSN - 1569-9293
pISSN - 1569-9285
DOI - 10.1093/icvts/ivaa334
Subject(s) - medicine , lung cancer , meta analysis , thoracotomy , surgery , confidence interval , stage (stratigraphy) , cardiothoracic surgery , survival rate , carcinoma , oncology , paleontology , biology
Optimal treatment of stage IIIA (N2) non-small-cell lung cancer (NSCLC) is controversial. Guidelines advise induction therapy before surgical resection. A proportion of patients with cN0 NSCLC are postoperatively upstaged due to unsuspected N2 disease. Survival of unsuspected N2 NSCLC treated with surgery varies and technical feasibility of video-assisted thoracic surgery (VATS) is unknown. The purpose of this study was to assess prevalence and survival of unsuspected N2 NSCLC treated with thoracotomy or VATS.