Oncological outcomes of unsuspected pN2 in patients with non-small-cell lung cancer: a systematic review and meta-analysis | Zendy

Michiel A IJsseldijk | Zendy; Richard P. G. ten Broek | Zendy; Bastiaan Wiering | Zendy; Edo J. Hekma | Zendy; Marnix A.J. de Roos | Zendy

Open Access

Oncological outcomes of unsuspected pN2 in patients with non-small-cell lung cancer: a systematic review and meta-analysis

Author(s) -

Michiel A IJsseldijk,

Richard P. G. ten Broek,

Bastiaan Wiering,

Edo J. Hekma,

Marnix A.J. de Roos

Publication year - 2020

Publication title -

interactive cardiovascular and thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 56

eISSN - 1569-9293

pISSN - 1569-9285

DOI - 10.1093/icvts/ivaa334

Subject(s) - medicine , lung cancer , meta analysis , thoracotomy , surgery , confidence interval , stage (stratigraphy) , cardiothoracic surgery , survival rate , carcinoma , oncology , paleontology , biology

Optimal treatment of stage IIIA (N2) non-small-cell lung cancer (NSCLC) is controversial. Guidelines advise induction therapy before surgical resection. A proportion of patients with cN0 NSCLC are postoperatively upstaged due to unsuspected N2 disease. Survival of unsuspected N2 NSCLC treated with surgery varies and technical feasibility of video-assisted thoracic surgery (VATS) is unknown. The purpose of this study was to assess prevalence and survival of unsuspected N2 NSCLC treated with thoracotomy or VATS.

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